Advanced Technologies for Cure

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Professor Nicholas James (left), Co-Theme Lead, Professor Vin Paleri (right), Co-Theme Lead, for Advanced Technologies for Cure
Professor Nicholas James (left), Co-Theme Lead, Professor Vin Paleri (right), Co-Theme Lead, for Advanced Technologies for Cure

Theme overview

Improving treatments that target the primary site of the cancer, such as radiation therapy and surgery for patients with early-stage cancer. We will also evaluate new therapies delivered as injections.

Surgery and radiotherapy are effective treatments that lead to many people being cured of cancer if at an early-stage. 

Our researchers are investigating ways to improve radiotherapy and surgery, whilst developing new treatments delivered by injection directly to the site of the cancer. They think this will increase survival rates, reduce negative side effects, and shorten treatment durations. 

Theme aims

We aim to:

  • Cure more patients with shorter, less toxic radiotherapy doses.
  • Expand the role precision surgery can play in curing different cancers.
  • Develop locally-injectable therapies to complement surgery and radiotherapy, helping treatment to be more successful.
  • Use the above technologies to treat people with limited cancer spread, considered incurable until now.
  • Design inclusive trials so that our research participation includes those from underserved populations.

Co-Theme Leads

Professor Nicholas James is a Professor of Prostate and Bladder Cancer Research at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust . His interests are in clinical trials in advanced prostate cancer and bladder preservation with chemo-radiation for locally advanced bladder cancer.

Professor Vinidh Paleri is a Consultant Head and Neck Surgeon at The Royal Marsden NHS Foundation Trust and Director of The International Centre for Recurrent Head and Neck Cancer. He is also Professor of Head and Neck Surgery at The Institute of Cancer Research. His special interest is in transoral robotic surgery, and he has accrued the largest experience in transoral robotic surgery in the UK.